更新時(shi)間：2023-07-28
點擊化學 Alkynyl Palmitic Acid：Alkynyl Palmitic Acid 是一種 PROTAC linker，屬(shu)于 alkyl chain 類。可用于合成 PROTAC 分子。Alkynyl Palmitic Acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PR
點擊化學 Alkynyl Palmitic Acid
炔(gui)(gui)基(ji)(ji)肉豆蔻(kou)酸(suan)可用于鑒定和(he)表(biao)征翻譯(yi)后(hou)的(de)肉豆蔻(kou)基(ji)(ji)化蛋(dan)白(bai)質 炔(gui)(gui)基(ji)(ji)棕(zong)(zong)櫚(lv)(lv)酸(suan)（15-十六烷酸(suan)或(huo)棕(zong)(zong)櫚(lv)(lv)酸(suan) (15-yne)）是一種修飾(shi)的(de)棕(zong)(zong)櫚(lv)(lv)酸(suan)，帶有 ω-末端炔(gui)(gui)烴。 炔(gui)(gui)基(ji)(ji)棕(zong)(zong)櫚(lv)(lv)酸(suan)通(tong)常用于使用強大(da)的(de)點(dian)擊化學識別和(he)表(biao)征蛋(dan)白(bai)質的(de)翻譯(yi)后(hou) S-棕(zong)(zong)櫚(lv)(lv)酰化。.
Alkynyl myristic acid is can be used to identify and characterize the post-translational myristylated proteins Alkynyl palmitic acid (15-hexadecynoic acid or Palmitic acid (15-yne)) is a modified palmitic acid with an ω-terminal alkyne. Alkynyl palmitic acid often used to identify and characterize the post-translational S-palmitoylation of proteins using the powerful click chemistry (see References).
結構式 ：
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點擊化學 Alkynyl Palmitic Acid相關產品
Alkyne-PEG4-Acid | TA102-100 | 100 mg | $195 | click chemistry tools |
Cy5 NHS Ester | 1076-1 | 1 mg | $105 | click chemistry tools |
Cy7 NHS Ester | 1115-1 | 1 mg | $105 | click chemistry tools |
Click-&-Go™ Plus 405 Labeling Kit | 1313 | 1kit | $219 | click chemistry tools |
Click-&-Go™ Plus 546 Labeling Kit | 1316 | 1kit | $219 | click chemistry tools |
Click-&-Go™ Plus 647 Labeling Kit | 1320 | 1kit | $219 | click chemistry tools |
參考文獻
1. Gray, R. A. V., et al. (2021). Optimized Incorporation of Alkynyl Fatty Acid Analogs for the Detection of Fatty Acylated Proteins using Click Chemistry. JoVE Journal, 10 (3791), 62107.
2. Li, B., et al. (2020). TMEM132A, a Novel Wnt Signaling Pathway Regulator Through Wntless (WLS) Interaction. Front Cell Dev Biol., 8, 599890.
3. Lee, M.T., et al. (2020). Dietary sphinganine is selectively assimilated by members of themammaliangut microbiome. J Lipid Res .
4. White, F. K. H., et al. (2019). S-Palmitoylation of junctophilin-2 is critical for its role in tethering the sarcoplasmic reticulum to the plasma membrane. J Biol Chem., 294 (36), 13487-13501.
