Doccol是一家美國生(sheng)物(wu)技術公司，從解決生(sheng)物(wu)研(yan)究(jiu)(jiu)中(zhong)(zhong)的(de)(de)實(shi)際問題開始。2004年，Doccol發現了實(shi)驗(yan)(yan)性卒(zu)中(zhong)(zhong)研(yan)究(jiu)(jiu)的(de)(de)關鍵問題之一是卒(zu)中(zhong)(zhong)模型(xing)(xing)(xing)的(de)(de)質量(liang)不(bu)一致(zhi)，因此(ci)通過提(ti)(ti)供(gong)(gong)標準(zhun)化的(de)(de)封(feng)堵(du)器，即硅橡膠(jiao)涂(tu)(tu)層(ceng)單(dan)絲(si)，用(yong)(yong)(yong)于(yu)大腦中(zhong)(zhong)動脈(mo)閉塞（MCAO），為(wei)(wei)此(ci)提(ti)(ti)供(gong)(gong)了解決方案。這些MCAO封(feng)堵(du)器深受(shou)中(zhong)(zhong)風(feng)科研(yan)人(ren)(ren)(ren)員(yuan)的(de)(de)喜愛(ai)，并(bing)被命(ming)名為(wei)(wei)“MCAO縫合線(xian)(xian)"。 我(wo)們精(jing)致(zhi)的(de)(de)硅橡膠(jiao)涂(tu)(tu)層(ceng)單(dan)絲(si)是專門為(wei)(wei)誘(you)(you)(you)導MCAO腔內(nei)(nei)燈絲(si)模型(xing)(xing)(xing)而設計制造(zao)的(de)(de)，該模型(xing)(xing)(xing)已被廣泛(fan)用(yong)(yong)(yong)于(yu)體(ti)內(nei)(nei)實(shi)驗(yan)(yan)性腦卒(zu)中(zhong)(zhong)研(yan)究(jiu)(jiu)。使用(yong)(yong)(yong) Doccol MCAO 縫合線(xian)(xian)誘(you)(you)(you)導卒(zu)中(zhong)(zhong)模型(xing)(xing)(xing)將(jiang)(jiang)通過減(jian)少不(bu)全部閉塞和顱內(nei)(nei)出血的(de)(de)發生(sheng)來(lai)提(ti)(ti)高(gao)模型(xing)(xing)(xing)質量(liang)。使用(yong)(yong)(yong)Doccol MCAO縫合線(xian)(xian)，您將(jiang)(jiang)能(neng)夠實(shi)現高(gao)度一致(zhi)的(de)(de)梗(geng)死(si)以及(ji)低死(si)亡率。除了認(ren)可的(de)(de)產品質量(liang)外(wai)，Doccol還為(wei)(wei)MCAO縫合線(xian)(xian)提(ti)(ti)供(gong)(gong)了種類繁多的(de)(de)縫合線(xian)(xian)，旨在滿足中(zhong)(zhong)風(feng)研(yan)究(jiu)(jiu)人(ren)(ren)(ren)員(yuan)的(de)(de)各種需求。多年來(lai)，我(wo)們的(de)(de)MCAO縫合線(xian)(xian)一直被中(zhong)(zhong)風(feng)研(yan)究(jiu)(jiu)人(ren)(ren)(ren)員(yuan)優選(xuan)用(yong)(yong)(yong)于(yu)誘(you)(you)(you)導中(zhong)(zhong)風(feng)模型(xing)(xing)(xing)。據報(bao)道，使用(yong)(yong)(yong)Doccol MCAO縫合線(xian)(xian)誘(you)(you)(you)導MCAO模型(xing)(xing)(xing)能(neng)夠將(jiang)(jiang)梗(geng)死(si)體(ti)積的(de)(de)標準(zhun)偏差降低到其(qi)相應(ying)平均值的(de)(de)5%; 這種建模方法(fa)正在成為(wei)(wei)確保MCAO模型(xing)(xing)(xing)最高(gao)質量(liang)的(de)(de)新標準(zhun)。欲了解更多信息，中(zhong)(zhong)國客戶請聯系美國Doccol在中(zhong)(zhong)國的(de)(de)總代(dai)理(li)靶點科技。

2010年，Doccol注(zhu)意到(dao)(dao)大多數實驗(yan)室進行的(de)(de)(de)微血(xue)管導(dao)(dao)管插入術對于血(xue)液(ye)檢測(ce)和藥物輸送都不方便。這些“微導(dao)(dao)管"有(you)一個(ge)需要(yao)針頭連接(jie)的(de)(de)(de)過(guo)渡管，當壓(ya)力高(gao)時(shi)可(ke)能會斷裂(lie)，并且(qie)可(ke)能會意外刺入操作(zuo)員的(de)(de)(de)手指，然(ran)后才能連接(jie)到(dao)(dao)合成器。這些導(dao)(dao)管也有(you)很大的(de)(de)(de)內部容積(ji)，必(bi)須處理(li)(li)才能輸送藥物。Doccol 提(ti)供專門(men)設(she)計的(de)(de)(de)微導(dao)(dao)管，用于提(ti)高(gao)嚙(nie)齒動物血(xue)液(ye)采樣、藥物輸送、小流(liu)速(su)液(ye)體轉移(yi)和生理(li)(li)監測(ce)的(de)(de)(de)性能、質(zhi)量和生產率，其中需要(yao)侵入性血(xue)管通(tong)路。我們的(de)(de)(de)微導(dao)(dao)管連接(jie)到(dao)(dao)工業(ye)標準(zhun)的(de)(de)(de)魯爾鎖或旋塞(sai)閥，因此消除了(le)過(guo)渡管和針頭連接(jie)，也大大減少了(le)內部體積(ji)。Doccol 為所有(you)常見部位的(de)(de)(de)血(xue)管插管提(ti)供了(le)足(zu)夠的(de)(de)(de)微導(dao)(dao)管選擇，例如(ru)尾靜脈、股靜脈、頸靜脈和臂靜脈和動脈，以(yi)及頸靜脈。

在Doccol多年來(lai)致(zhi)力于(yu)中(zhong)風研(yan)究(jiu)期間，Doccol 還開始提(ti)供精心挑(tiao)選(xuan)的(de)基本顯(xian)微手術工(gong)具(ju)和(he)設備(bei)，并(bing)于(yu) 2019 年開發(fa)了(le)其不(bu)同的(de)基于(yu) Arduino 的(de) PID 溫度(du)控制(zhi)器。這(zhe)些工(gong)具(ju)和(he)設備(bei)可確保您(nin)的(de)實驗性中(zhong)風研(yan)究(jiu)具(ju)有高質量和(he)高生產(chan)率。

Doccol is a biotech company that started from solving real problems in biological research. In 2004, Doccol identified one of the key problems in experimental stroke research is the inconsistent quality of stroke models, and thence provided a solution for this by offerring standardized occluders, the silicone rubber-coated monofilaments,  for middle cerebral artery occlusion (MCAO). Those MCAO occluders  were liked very much by stroke reaearchers and given the name "MCAO sutures".  Our delicate silicone rubber-coated monofilaments are specially designed and manufactured for inducing the intraluminal filament model of MCAO, which has been widely used for in vivo experimental stroke studies. Using Doccol MCAO sutures for inducing stroke models will improve your model quality by reducing the occurrence of both the incomplete occlusion and the intracranial bleeding. With Doccol MCAO sutures, you will be able to achieve a highly consistent infarct as well as a low mortality rate. In addition to the super product quality, Doccol provides MCAO sutures with a great variety that was designed to meet the diverse demand from stroke investigators. For many years our MCAO sutures have been preferably selected by stroke investigators for inducing stroke models. Using Doccol MCAO sutures for inducing MCAO models has been reported to be able to reduce the standard deviation to 5% of its corresponding mean value as for infarction volume; and this modeling method is becoming a methodological new standard for ensuring the highest quality of MCAO models. For more information please read Doccol Made a Difference in Stroke Modeling.

In 2010, Doccol noticed that microvascular catheterization procedures performed in most laboratories are inconvinient for both blood testing and drug delivery. Those "microcatheters" have a transition tubing requiring a needle connection, which may break when pressure is high, and may accidentally puncture into the operator's finger, before it can be connected to a synringe. These catheters also have a large inner volume that has to be dealt with for drug delivery. Doccol offerred specially designed microcatheters for improving performance, quality and productivity in rodent blood sampling, drug delivery, small flow rate liquid transferring, and physiological monitoring, in which invasive vascular access is necessary. Our microcatheters are permanently connected to an industrial standard Luer lock or stopcock, therefore, eliminated the transitional tubing and needle connection and also dramatically reduced inner volume. Doccol provides sufficient choices of micro catheters for vascular cannulation in all common locations, such as the tail, femoral, carotid, and brachial veins and arteries, and also the jugular veins.

During years of our dedicated services in stroke research, Doccol also started to provide our carefully-selected essential microsurgical tools and devices, and in 2019 Doccol developed its unique Arduino-based PID temperature controllers. These essential tools and devices ensure your experimental stroke research with high quality and high productivity.

靶(ba)點科技（北京）有限公(gong)司(si)(si)（Target Technology (Beijing) Co.,Ltd.），成立于2016年，是由一群來自歐洲荷蘭的留(liu)學海(hai)歸和(he)高(gao)校及研(yan)究所博士人員創(chuang)辦的生(sheng)物高(gao)科技公(gong)司(si)(si)。公(gong)司(si)(si)基(ji)于四個平臺(tai)技術(shu)TargoSome^®（脂(zhi)質體靶向(xiang)技術），TargoChem^®（化合物靶向技術），TargoAnti^®（抗(kang)體靶向技術(shu)）和TargoNano^®（納米靶(ba)向技術），研(yan)發了靶(ba)向細(xi)胞的(de)遞送(song)系統。

公司注重(zhong)轉化醫學，強化“Bench-to-Bedside"的基礎產品開(kai)發。目(mu)前，靶點(dian)科技已經(jing)成為單核巨噬細胞系統研(yan)究領(ling)域的(de)樹(shu)立良好口碑，能夠給研(yan)究人員提供各種模擬人類疾(ji)病的(de)動物(wu)模型的(de)制備，公(gong)司團(tuan)隊對單核巨噬細胞系統有(you)著深刻的(de)認識和理(li)解(jie)，從標記，分(fen)離(li)，富集，純化，培養和細胞清除，形態識別(bie)等(deng)提供一整套綜合(he)解(jie)決方案。

基于對靶點科技（北京）有限公司的認同，自2022年11月29日期，靶點科技被美國Doccol公司授權為中國總代理。客戶通過靶點科技購買美國Doccol公(gong)司的產品，質量可靠，渠道合法，售后無憂。大腦中動(dong)脈阻(zu)塞(sai)(MCAO)造模是研究缺血性腦(nao)卒(zu)中(zhong)的經典動物模型，Doccol是MCAO造模國(guo)際廣(guang)泛(fan)使用(yong)的栓線(xian)品(pin)牌，文獻數以萬計。

靶點(dian)科(ke)技始終(zhong)秉(bing)承(cheng)“Bench to Bedside"的出發點(dian)，“專業⁺專注⁺"的(de)服(fu)務宗旨，以“Hit Your Target^®"為(wei)(wei)目標， 竭力為(wei)(wei)客戶提(ti)供“Proven and Published^®"的(de)一攬(lan)子綜合解決方案，將(jiang)為(wei)實現這一美(mei)好愿景而(er)努力奮斗(dou)。