德國Emfret公(gong)司專注心血(xue)管和血(xue)液系統研(yan)究用抗體研(yan)發(fa)和生產，供(gong)應(ying)的抗(kang)體包括清除血(xue)液(ye)中血(xue)小(xiao)板、流式(shi)細胞術(shu)鑒定分析小(xiao)鼠血(xue)小(xiao)板表面糖蛋白，emfret公(gong)司的抗(kang)體不僅適(shi)用于(yu)流失分析、WB檢(jian)測(ce)，還可用于(yu)免疫組化/免疫熒光及免疫共沉(chen)淀檢(jian)測(ce)。

背景資料：

This antibody preparation contains a mixture of purified rat monoclonal antibodies directed against mouse GPIb (CD42b). Targeting of this receptor with divalent IgGs results in profound and irreversible Fc-independent platelet depletion in mice1,2 . Platelet depletion is frequently used to study the general role of platelets in (patho-) physiology3 .

保存條件：

The antibodies were purified from hybridoma cell culture supernatant by Protein G-Sepharose chromatography.

Stable for six months from date of shipment when stored at 4°C.

KEEP STERILE, the preparation contains no preservative. Aliquots can be stored at -20°C for at least one year. Avoid repeated freezing and thawing.

應用：

This preparation is optimized to reduce the platelet count by >95% within 60 minutes after intravenous injection of 2 µg/g bodyweight. It is recommended to inject the antibodies in a volume of 100-200 µl (diluted with sterile PBS).

同型對照（抗體來源）： Rat IgG (Wistar)

緩沖液： 0.5 mg purified immunoglobulins in PBS, 0.2% (w/v) BSA, sterile filtered

濃度： 0.5 mg/ml

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